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HOME>>About CTC Tuesday, April 24 2018


Studies Seeking Volunteers
    For more information on studies being conducted at the WRAIR CTC,
    call 1-866-4-CTC-STUDY (866-428-2788)
    or click here to send a confidential email to one of our recruiters.



    Dengue Vaccine Study #2453

    Dengue is a common infection affecting residents and travelers to many areas of the world. The purpose of this study is to compare two different vaccination schedules by collecting information about the safety of these vaccines and seeing how well each of the vaccine schedules trigger an immune response against dengue.

    If you choose to participate in this study, you will receive one dose of each of the vaccines. Each vaccine will be given in your upper arm using a needle, and blood samples will be collected throughout the study to look at your body's response to the vaccine. All study volunteers will be paid for their participation in this study.

    Click here for more information on our dengue study.

    • Study Duration: Approximately 15-18 months (depending on your group assignment)
    • Number of Clinic Visits: 14
    • Screening Dates: weekday mornings between 6:00am & 10:00am*
    • *Please call 1-866-428-2788 to schedule a screening appointment


    • To be eligible for this study, you:
    • MUST be 18 to 42 years of age
    • MUST be in good health and have NO significant medical conditions or diseases
    • MUST have NEGATIVE blood tests for hepatitis B, hepatitis C and HIV
    • MUST be willing to attend ALL of the required visits over the next 15-18 months
    • MUST be willing to refrain from participation in any other clinical studies involving investigational drugs or vaccines while participating in this study
    • MUST be willing to use a reliable form of birth control during the study
    • CANNOT be pregnant, breastfeeding or planning to become pregnant during the study
    • CANNOT have ever had a dengue infection or received a dengue vaccine
    • CANNOT have donated or received blood, blood products, or plasma within 90 days prior to starting the study or plan on donating blood or plasma during the study

    NOTE: There may be other reasons why you cannot participate in this study.

    Malaria Challenge Study #2345

    We are currently seeking volunteers to enroll in an ongoing malaria study as infectivity controls. Over the last year, 130 volunteers were vaccinated with an investigational malaria vaccine. In June, these vaccinated volunteers will be challenged to see if the vaccine protects them from malaria infection. The challenge involves being bitten by mosquitoes infected with the malaria parasite.

    Infectivity controls will not be vaccinated, but will participate in the malaria challenge only. This is necessary to show that the mosquitoes are carrying the malaria parasite. Infectivity controls will develop malaria from the mosquito bites. Immediately upon diagnosis of malaria, volunteers will be treated with an FDA-approved medication and will be completely cured. All study volunteers will be paid for their participation in this study.

  • Click here for more information on being a malaria control.

    • Study Duration: 28 days (not including screening visit)
    • Study Start Date: June 4-8, 2018
    • Screening Dates: weekday mornings between 6:00am & 10:00am (starting April 16, 2018)*
    • *Please call 1-866-428-2788 to schedule a screening appointment


    • To be eligible for this study, you:
    • MUST be a healthy male or non-pregnant, non-breastfeeding female (both civilian & military can enroll in this study)
    • MUST be between the ages of 18 and 55
    • MUST have no plans to travel outside of the DC metro area while enrolled in the study
    • MUST be a low cardiac risk
    • CANNOT have had malaria within the last 5 years
    • CANNOT have EVER received an investigational malaria vaccine
    • CANNOT have taken medication to prevent malaria within the past 60 days
    • CANNOT have heart, lung, liver, or kidney disease (high blood pressure, diabetes)
    • CANNOT have neurologic disease
    • CANNOT have had your spleen removed
    • CANNOT have history of sickle cell disease or other blood diseases such as HIV or viral hepatitis
    • CANNOT be pregnant or have plans to become pregnant during the study time period

    NOTE: There may be other reasons why you cannot participate in this study.

    ETEC Vaccine Study #2445

    This study involves an investigational enterotoxigenic Escherichia coli or ETEC vaccine. ETEC is a bacteria that causes diarrhea in people who live in or travel to certain foreign countries. The goals of this study are to test the safety of increasing doses of the vaccine and to evaluate the immune response (or infection fighting ablity) after vaccination.

    If you choose to participate in this study, you will receive a series of three vaccinations, given into the muscle of the upper arm using a needle and syringe. These vaccines cannot give you the ETEC infection, because they do not contain actual ETEC. All study volunteers will be paid for their participation in this study.

  • Click here for more information on our ETEC study.

    • Study Duration: 70 days (not including screening visit)
    • Number of Visits: 13 clinic visits + 2 phone calls
    • Study Start Dates: (group A) - FILLED
    • ________________.(group B) - FILLED
    • ________________.(group C) - July 10, 2018
    • ________________.(group D) - September 2018
    • ________________.(group E) - January 2019
    • Screening Dates: weekday mornings between 6:00am & 10:00am (starting April 17, 2018)*
    • *Please call 1-866-428-2788 to schedule a screening appointment


    • To be eligible for this study, you:
    • MUST be a healthy adult between the ages of 18 and 45
    • MUST (for women) agree to use effective and reliable birth control methods throughout the study
    • MUST be able to come to all clinic visits
    • MUST be be willing to refrain from participation in any other clinical studies involving investigational drugs or vaccines while participating in this study
    • CANNOT (for women) be pregnant or breastfeeding. You should also avoid pregnancy or breastfeeding for 3 months after last vaccine dose.
    • CANNOT have been previously exposed to ETEC bacteria in the past 3 years, such as a past infection, an earlier research study, or through your work
    • CANNOT have a positive blood test for Hepatitis B, Hepatitis C, or HIV (the virus that causes AIDS)
    • CANNOT have certain chronic skin diseases or active skin infection
    • CANNOT have abnormal bowel habits (fewer than 3 per week or more than 3 loose stools per day)
    • CANNOT regularly use constipation, antacid, or anti-diarrhea medications

    NOTE: There may be other reasons why you cannot participate in this study.


If you think you qualify for one of the above studies and you would like schedule a screening appointment to see if you are eligible to enroll, please contact us today!


Sincerely,

The Clinical Trials Center Team

Call: 866-4-CTC-STUDY (866-428-2788)
Text: 301-215-0388
Email: usarmy.detrick.medcom-wrair.mbx.clinical-trials@mail.mil
Business Hours: Monday-Friday, 6:00am-2:30pm




This page last updated on: 03 April 2018


Last Modified Date: 16-March-2017



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